An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID.

PHASE4CompletedINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

October 8, 2024

Primary Completion Date

September 17, 2025

Study Completion Date

September 17, 2025

Conditions
SARS-CoV-2 InfectionCOVID-19
Interventions
DRUG

Remdesivir

"Remdesivir is a prodrug that is intended to allow intracellular delivery of GS-441524 monophosphate and subsequent biotransformation into GS-441524 triphosphate, a ribonucleotide analogue inhibitor of viral RNA polymerase.~Participants will receive a single loading dose of 200 milligrams of Remdesivir in 250ml sodium chloride 0.9% bag via IV over 60 minutes on day 1, followed by, on days 2 - 5, a dose of 100 milligrams of Remdesivir in 250ml sodium chloride 0.9% bag via IV once daily over 30 minutes."

Trial Locations (4)

DE22 1GB

University of Derby, Derby

S42 7JE

Derbyshire Community Health Services NHS Foundation Trust, Chesterfield

D22 3NE

Royal Derby Hospital (UHDB), Derby

EX4 4PY

University of Exeter / Royal Devon University Healthcare NHS FT, Exeter

All Listed Sponsors
collaborator

University of Exeter

OTHER

collaborator

University of Plymouth

OTHER

collaborator

University Hospitals of Derby and Burton NHS Foundation Trust

OTHER

collaborator

Aston University

OTHER

collaborator

Royal Devon and Exeter NHS Foundation Trust

OTHER

lead

University of Derby

OTHER

NCT05911906 - An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID. | Biotech Hunter | Biotech Hunter