Optimizing Access Surgery In Senior Hemodialysis Patients

NAActive, not recruitingINTERVENTIONAL
Enrollment

166

Participants

Timeline

Start Date

November 1, 2019

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Vascular Access ComplicationHemodialysis Access FailureDialysis Access MalfunctionArteriovenous FistulaArteriovenous GraftCentral Venous Catheter Related Bloodstream Infection
Interventions
PROCEDURE

Arteriovenous fistula creation

It is recommended to create the arteriovenous fistula 3 to 6 months before the expected start of hemodialysis treatment using locoregional anesthesia. It is recommended to use minimal venous and arterial diameters of 2mm for radiocephalic fistulas and 3mm for brachiocephalic and brachiobasilic fistulas. It is recommended to avoid creating an arteriovenous fistula at the same side as a pacemaker, central venous catheter, or arterial stenosis. It is recommended to use the following order of preference for arteriovenous fistula creation: radiocephalic fistula as first choice, brachiocephalic fistula as second choice, and brachiobasilic fistula as third choice.

PROCEDURE

Arteriovenous graft placement

It is recommended to implant the arteriovenous graft 2 weeks before the expected start of hemodialysis treatment under antibiotic prophylaxis. Implantation of an early-cannulation graft is recommended for patients who require more urgent start of hemodialysis to avoid the use of a temporary central venous catheter. It is recommended to use minimal arterial and venous diameters of 3mm and 4mm, respectively. It is recommended to avoid placing an arteriovenous graft at the same side as a pacemaker, central venous catheter, or arterial stenosis.

PROCEDURE

Central venous catheter placement

It is recommended to place a tunneled central venous catheter just before the start of hemodialysis treatment under local anesthesia, with conscious sedation if preferred by the patient. The catheter should preferably be placed in the right internal jugular vein with ultrasound-guided puncture and fluoroscopy control under sterile conditions. According to usual practice at the trial center, catheters may be implanted by surgeons, interventional radiologists, or nephrologists.

Trial Locations (20)

Unknown

Noordwest Ziekenhuisgroep, Alkmaar

Ziekenhuisgroep Twente, Almelo

OLVG, Amsterdam

Rijnstate Ziekenhuis, Arnhem

Amphia Ziekenhuis, Breda

Albert Schweitzer Ziekenhuis, Dordrecht

Catharina Ziekenhuis Eindhoven, Eindhoven

Medisch Spectrum Twente, Enschede

Spaarne Gasthuis, Haarlem

Zuyderland Medisch Centrum, Heerlen

Medisch Centrum Leeuwarden, Leeuwarden

Leids Universitair Medisch Centrum, Leiden

Maastricht University Medical Center, Maastricht

Canisius Wilhelmina Ziekenhuis, Nijmegen

Franciscus Gasthuis & Vlietland, Rotterdam

Haaglanden Medisch Centrum, The Hague

Elisabeth Tweesteden Ziekenhuis, Tilburg

Maxima Medisch Centrum, Veldhoven

Viecuri Medisch Centrum, Venlo

Isala Klinieken, Zwolle

All Listed Sponsors
collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

lead

Maastricht University Medical Center

OTHER