Envafolimab Plus Docetaxel In Combination With or Without Trilaciclib Versus Docetaxel in Advanced NSCLC

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

132

Participants

Timeline

Start Date

July 1, 2023

Primary Completion Date

December 30, 2025

Study Completion Date

June 30, 2026

Conditions
Advanced Non-Small Cell Lung Cancer
Interventions
DRUG

Trilaciclib+Envafolimab+Docetaxel

This is a multi-arm, randomized, controlled, multicenter, Phase II clinical study. Participants randomly assigned at a 1:1:1 ratio to three groups, and will be treated until disease progression, intolerance, withdrawal of consent or completion determined by the investigator.

DRUG

Envafolimab+Docetaxel

This is a multi-arm, randomized, controlled, multicenter, Phase II clinical study. Participants randomly assigned at a 1:1:1 ratio to three groups, and will be treated until disease progression, intolerance, withdrawal of consent or completion determined by the investigator.

DRUG

Docetaxel

This is a multi-arm, randomized, controlled, multicenter, Phase II clinical study. Participants randomly assigned at a 1:1:1 ratio to three groups, and will be treated until disease progression, intolerance, withdrawal of consent or completion determined by the investigator.

All Listed Sponsors
lead

Fudan University

OTHER

NCT05910034 - Envafolimab Plus Docetaxel In Combination With or Without Trilaciclib Versus Docetaxel in Advanced NSCLC | Biotech Hunter | Biotech Hunter