A First-In-Human Trial of pTTL in Advanced Colorectal Cancer

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

March 15, 2023

Primary Completion Date

December 31, 2027

Study Completion Date

June 30, 2032

Conditions
Colorectal Cancer
Interventions
DRUG

pTTL

pTTL is an autologous cell product for adoptive cancer immunotherapy containing in vitro expanded T cells stimulated with patient-specific tumour neoantigens derived from tumour-draining lymph nodes.

Trial Locations (2)

17176

RECRUITING

Medical Unit Cell therapy and Allogeneic Stem cell Transplantation (ME CAST), and the Center for Clinical Cancer studies - Phase 1 unit, Karolinska University Hospital, Stockholm

723 35

RECRUITING

Unit for Colorectal Surgery, Dept. of Surgery, Västmanlands Sjukhus Västerås, Västerås

Sponsors
All Listed Sponsors
collaborator

CTC Clinical Trial Consultants AB

INDUSTRY

collaborator

Karolinska University Hospital

OTHER

collaborator

Region Västmanland

OTHER

collaborator

Vecura

UNKNOWN

lead

Neogap Therapeutics AB

INDUSTRY