Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 Deficiency

15 mg/kg IV three times per day starting on day +5 until approximately day +30 (+/- 2 days)

0.02 mg/kg IV daily starting on day +5

50 mg/kg IV daily on days +3 and +4

200cGy on day -1

stem cell transplant on day 0

Single 0.6 mg/kg IV infusion administered between days -13 and day -10

14.5 mg/kg IV daily on days -6 and -5; for 7/8 Unrelated or Haploidentical Donor, prior to transplant.

30 mg/m2 IV over 30 minutes daily. For 8/8 Matched Related or Unrelated Donor, fludarabine dose will be on days -4, -3, and -2. For 7/8 Unrelated or Haploidentical Donor, fludarabine dose will be on days -6, -5, -4, -3, and -2.