76
Participants
Start Date
July 1, 2023
Primary Completion Date
July 1, 2026
Study Completion Date
November 1, 2026
Decitabine
Decitabine 6 mg/m2 daily subcutaneously for consecutive 3 days (day 1 to day 3)
Granulocyte Colony-Stimulating Factor
5ug/kg/d when absolute neutrophil count ≤ 1.5 × 109/L
Thrombopoietin Receptor Agonist
Eltrombopag initial dose: 25 mg orally once a day, may increase to up to 75 mg/day, when platelet count ≤ 30 × 109/L; Avatrombopag initial dose: 20 mg orally once a day, may increase to up to 60 mg/day, when platelet count ≤ 30 × 109/L.
Recombinant human erythropoietin
10000 U/day when hemoglobin ≤ 85 g/L
The First Affiliated Hospital of Soochow University
OTHER