NCT05907213View on ClinicalTrials.gov

Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1)

PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

September 25, 2023

Primary Completion Date

June 26, 2024

Study Completion Date

September 19, 2024

Conditions
Pain, PostoperativeDepression, Postpartum
Interventions
DRUG

Ketamine (Ketalar) Dose Level 1

Loading Dose: 0.05 mg/kg/hr X 1 hour; Maintenance Dose 0.05 mg/kg/hr x 12 hours

DRUG

Ketamine (Ketalar) Dose Level 2

Loading Dose: 0.08 mg/kg/hr X 1 hour; Maintenance Dose 0.05 mg/kg/hr x 12 hours

DRUG

Ketamine (Ketalar) Dose Level 3

Loading Dose: 0.12 mg/kg/hr X 1 hour; Maintenance Dose 0.05 mg/kg/hr x 12 hours

DRUG

Ketamine (Ketalar) Dose Level 4

Loading Dose: 0.18 mg/kg/hr X 1 hour; Maintenance Dose 0.05 mg/kg/hr x 12 hours

Trial Locations (1)

15213

Magee Womens Hospital of UPMC, Pittsburgh

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Grace Lim, MD, MS

OTHER

NCT05907213 - Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1) | Biotech Hunter | Biotech Hunter