20
Participants
Start Date
October 1, 2023
Primary Completion Date
September 30, 2026
Study Completion Date
March 31, 2027
Canagliflozin and Gemcitabine
"on the first, 8th and 15th day of treatment, patients were given intravenous drip of 1000mg/m2 gemcitabine, and 21 days was a course of treatment, lasting for 6 courses.~Take 400mg canagliflozin orally every day, and continue to use it until the end of chemotherapy. According to the patient's tolerance to disulfiram, the dose of canagliflozin can be re-evaluated during the treatment, and the highest dose is 125mg per day. The clinical symptoms, signs and adverse reactions of patients were observed, and the treatment effect of patients was evaluated after two consecutive cycles with 4 weeks as a cycle"
Gemcitabine
on the first, 8th and 15th day of treatment, patients were given 1000mg/m2 gemcitabine intravenously, and 21 days was a course of treatment, lasting for 6 courses.
Hangzhou first people's Hospital, Hangzhou
College of Pharmaceutical Sciences at Zhejiang University
UNKNOWN
The Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University
UNKNOWN
Zhang Xiaofeng,MD
OTHER