Uterine Preservation Via Lifestyle Transformation

PHASE2RecruitingINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

October 24, 2024

Primary Completion Date

October 31, 2028

Study Completion Date

October 31, 2029

Conditions
Endometrial HyperplasiaGrade 1 Endometrial Cancer
Interventions
BEHAVIORAL

Telemedicine behavioral weight intervention

Weekly telephone calls during the first month, biweekly during the next 5 months, and then monthly for the last 7 months (12 months total). Each telephone session will be 30 minutes long.

DRUG

Progestin

Released via the levonorgestrel-releasing IUD.

BEHAVIORAL

Enhanced usual care

1-3 page handouts

DRUG

Levonorgestrel-releasing IUD.

Standard of care

Trial Locations (3)

63110

RECRUITING

Washington University School of Medicine, St Louis

73104

RECRUITING

University of Oklahoma, Oklahoma City

87106

RECRUITING

University of New Mexico, Albuquerque

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Washington University School of Medicine

OTHER