Contribution of an Antiviral Drug (Valaciclovir) in the Treatment of Generalized Periodontitis (Stage III or IV and Grade A, B or C): Prospective, Randomized and Double Blind Clinical Trial

PHASE3RecruitingINTERVENTIONAL
Enrollment

142

Participants

Timeline

Start Date

February 5, 2024

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2026

Conditions
Periodontitis Chronic Generalized Severe
Interventions
DRUG

Antiviral treatment with conventional non-surgical treatment

Valaciclovir, a antiviral treatment will be added to the conventional non-surgical treatment of generalized periodontitis. One gram per day will be administered during 28 days.

DRUG

Placebo with conventional non-surgical treatment

Placebo of valaciclovir (same composition, without active substance) will be added to the conventional non-surgical treatment of generalized periodontitis. One gram a day will be administered during 28 days.

Trial Locations (3)

13385

NOT_YET_RECRUITING

APHM, Marseille

35000

RECRUITING

CHU de Rennes, Rennes

06000

RECRUITING

CHU de Nice, Nice

All Listed Sponsors
lead

Centre Hospitalier Universitaire de Nice

OTHER