TEIPP Immunotherapy in Patients With NSCLC

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

September 29, 2021

Primary Completion Date

April 30, 2024

Study Completion Date

April 30, 2024

Conditions
Non Small Cell Lung Cancer
Interventions
DRUG

TEIPP24 (LRPAP7-30V-SLP vaccine in Montanide ISA-51)

Patients will receive three rounds of vaccination three weeks apart via one subcutaneous (SC) injection in an alternating limb. Patients in the extension cohort will receive the highest safest dose in combination with pembrolizumab (a CPI).These patients will receive three rounds of combination treatment with TEIPP24 vaccination and pembrolizumab every three weeks. Pembrolizumab will be administered as per standard of care.

Trial Locations (2)

2333ZA

Leiden University Medical Center, Leiden

3000 CA

Erasmus Medical Center, Rotterdam

Sponsors
All Listed Sponsors
lead

Erasmus Medical Center

OTHER

NCT05898763 - TEIPP Immunotherapy in Patients With NSCLC | Biotech Hunter | Biotech Hunter