Safety and Efficacy of Licaminlimab Ophthalmic Solution for the Treatment of Dry Eye Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

122

Participants

Timeline

Start Date

November 29, 2023

Primary Completion Date

March 27, 2024

Study Completion Date

March 27, 2024

Conditions
Dry Eye Disease
Interventions
DRUG

licaminlimab

ophthalmic solution 60 mg/mL Subjects will be randomized to receive licaminlimab eye drops three times daily (TID) for 6 weeks.

OTHER

vehicle of OCS-02

inert ophthalmic solution vehicle of OCS-02 Subjects will be randomized to receive vehicle eye drops three times daily (TID) for 6 weeks.

OTHER

Artificial tears

Subjects who quality after an initial screening were entered into a run-in phase where they received artificial tears to use three times daily (TID) for approximately 14 days.

Trial Locations (5)

16507

Oculis Investigative Site, Erie

28150

Oculis Investigative Site, Shelby

38119

Oculis Investigative Site, Memphis

80907

Oculis Investigative Site, Colorado Springs

92663

Oculis Investigative Site, Newport Beach

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

ORA, Inc.

INDUSTRY

lead

Oculis

INDUSTRY