Scot Sweet Study (Interaction of a Non-nutritive Sweetener With a High-fibre Weight Loss Diet)

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 12, 2023

Primary Completion Date

December 16, 2024

Study Completion Date

December 16, 2024

Conditions
Appetitive Behavior
Interventions
OTHER

Phase 1 Control

Control diet (30% Fat, 15% Protein, 55% Carbohydrate, Fibre rising from 10 to 16g/d). Fed to energy balance (1.5 x Resting Metabolic Rate, RMR).

OTHER

Phase 2 High Fibre Weight Loss

High Fibre Weight Loss diet (30% Fat, 15% Protein, 55% Carbohydrate). Fed to energy deficit (100% RMR). The quantity of fructo-oligosaccharides (FOS) will be fixed at 20g/day for all kcal levels with additional fibre coming from the diet provided. The FOS will be split over breakfast, lunch and dinner in drinks/yoghurts which will be compulsory to consume.

OTHER

Phase 3 High Fibre and Non-Nutritive Sweetener Weight Loss

High Fibre and Non-Nutritive Sweetener Weight Loss diet (30% Fat, 15% Protein, 55% Carbohydrate). Fed to energy deficit (100% RMR). The quantity of fructo-oligosaccharides (FOS) and non-nutritive sweetener (sucralose) will be fixed at 20g/day and 30mg/day respectively for all kcal levels with additional fibre coming from the diet provided. The FOS and sucralose will be split over breakfast, lunch and dinner in drinks/yoghurts which will be compulsory to consume.

Trial Locations (1)

AB25 2ZD

Rowett Institute, University of Aberdeen, Aberdeen

All Listed Sponsors
lead

University of Aberdeen

OTHER

NCT05892003 - Scot Sweet Study (Interaction of a Non-nutritive Sweetener With a High-fibre Weight Loss Diet) | Biotech Hunter | Biotech Hunter