Neoadjuvant Therapy With Toripalimab and JS004 Combined With Platinum-based Doublet Chemotherapy for Resectable or Potentially Resectable Stage III Non-small Cell Lung Cancer: A Randomised Controlled, Open-label, Phase 2 Trial

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

124

Participants

Timeline

Start Date

July 1, 2023

Primary Completion Date

July 1, 2025

Study Completion Date

July 1, 2030

Conditions
Stage III Non-small Cell Lung Cancer
Interventions
DRUG

Toripalimab

Specified dose on specified days.

DRUG

JS004

Specified dose on specified days.

DRUG

Pemetrexed

Specified dose on specified days.

DRUG

Nab-paclitaxel

Specified dose on specified days.

DRUG

Carboplatin

Specified dose on specified days.

PROCEDURE

Surgery

Patients with resectable tumor after neoadjuvant therapy will be treated with surgery.

All Listed Sponsors
lead

Shanghai Pulmonary Hospital, Shanghai, China

OTHER