Effect of Adding Lamotrigine to Sodium Valproate in Childhood Epilepsy: Clinicolabratory Study

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

July 29, 2024

Primary Completion Date

July 30, 2024

Study Completion Date

April 30, 2025

Conditions
EpilepsyLamotrigineSodium Valproate Adverse Reaction
Interventions
DRUG

Sodium Valproate 500 Mg Prolonged-Release Oral Tablet

sodium valproate tablet30 mg / kg / day , maximum 1500mg / day . LTG :

DRUG

Lamotrigine

lamotrigine tablet 0.5 mg/kg for 2 weeks in two divided doses , increased in 0.5mg/kg/day increments every 2weeks .

DEVICE

E.E.G

device recording of brain activity. During this painless test, small sensors are attached to the scalp to pick up the electrical signals produced by the brain. These signals are recorded by a machine and are looked at by a doctoris

All Listed Sponsors
lead

Assiut University

OTHER