NCT05880862View on ClinicalTrials.gov

Comparative Effectiveness of Initial OAB Treatment Options Among Older Women at High Risk of Falls

EARLY_PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

September 28, 2023

Primary Completion Date

November 30, 2025

Study Completion Date

December 31, 2025

Conditions
Urinary Bladder, OveractiveUrinary IncontinenceAccidental Falls
Interventions
BEHAVIORAL

Pelvic Floor Muscle Training

A 12-week, 6 visit, outpatient program of physical therapist delivered behavioral and pelvic floor muscle training (PFMT)

DRUG

Mirabegron

Individually titrated Mirabegron, starting at 25 mg daily and increased to 50 mg daily at 6-weeks, during the 12-week intervention period.

DRUG

Trospium Chloride

A 12-week course of Trospium XL -extended release, 60mg once daily.

Trial Locations (1)

77555

University of Texas Medical Branch at Galveston, Galveston

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

The University of Texas Medical Branch, Galveston

OTHER