Nasal Olfactory Stimulation and Its Effect on Respiratory Drive in Preterm Infants

NACompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

June 14, 2023

Primary Completion Date

January 24, 2025

Study Completion Date

January 24, 2025

Conditions
Apnea of PrematurityPrematurityInfant, Premature, Diseases
Interventions
OTHER

Aroma

The study intervention is an olfactory stimulation with vanilla or strawberry aroma. The aroma will be applied to the inner surface of the nCPAP mask of preterm infants using designated scent pens every 3-4 hours over a period of 12 hours. The two aromas will be applied in blocks of 5 consecutive infants (5 infants vanilla, 5 infants strawberry, and so forth).

OTHER

Placebo

During the control intervention, identically looking placebo pens will be used to apply a colored carrier solution (without aroma) to the inner surface of the nCPAP mask of preterm infants in the same manner.

Trial Locations (1)

8091

Department of Neonatology, Newborn Research, University Hospital and University of Zurich,, Zurich

All Listed Sponsors
collaborator

Bangerter-Rhyner Foundation

UNKNOWN

lead

University of Zurich

OTHER

NCT05878925 - Nasal Olfactory Stimulation and Its Effect on Respiratory Drive in Preterm Infants | Biotech Hunter | Biotech Hunter