Accelerated rTMS for Post-Stroke Apathy

PHASE1CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

April 30, 2025

Study Completion Date

April 30, 2025

Conditions
ApathyStroke SequelaeStroke (CVA) or TIAStroke/Brain AttackMotivationAbulia
Interventions
DEVICE

MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System

Treatment will consist 12 approximately-three-minute sessions on each of three treatment days within a seven-day period. To promote participant adherence and retention, treatment days will not need to be contiguous. A single session consists of 600 pulses delivered to the dmPFC at an intensity of 120% resting motor threshold (rMT). 50 hz triphasic bursts will be delivered for two seconds, followed by an 8 second inter-train interval. Trains will be repeated every 10 seconds, 10 times total, for a total of 190 seconds per session. An intersession interval of at least 15 minutes will be employed between each of the 12 sessions. Each treatment day will thus last approximately 3-4 hours in duration.

Trial Locations (1)

29403

Medical University of South Carolina Brain Stimulation Lab, Charleston

All Listed Sponsors
lead

Medical University of South Carolina

OTHER

NCT05878457 - Accelerated rTMS for Post-Stroke Apathy | Biotech Hunter | Biotech Hunter