2,978
Participants
Start Date
July 13, 2023
Primary Completion Date
January 15, 2024
Study Completion Date
March 30, 2024
Seasonal Malaria Chemoprophylaxis (under 5 year old) implemented by the MoH without DOT
Standard approach for SMC strategy used by the Ministry of Health (without directly-observed therapy) and without any interference of the study team. Implemented over 4 rounds, carried out in June-October 2023 with \~30 days between rounds.
Seasonal Malaria Chemoprophylaxis (under 5 years old) with DOT
SMC will be implemented with the same number of rounds and the same timing as in active comparator arm but village health workers will visit the participants at home to administer each dose of study treatment (with DOT-directly-observed therapy)
Seasonal Malaria Chemoprophylaxis (under 10 years old) with DOT
SMC will be implemented as in arm 2 but age of participants is extended up to 10 years: each dose of study treatment (with DOT-directly-observed therapy) distributed at home by village health workers.
Groupe de Recherche Action en Santé, Ouagadougou
Groupe de Recherche Action en Sante
OTHER
Radboud University Medical Center
OTHER
London School of Hygiene and Tropical Medicine
OTHER