Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

August 21, 2023

Primary Completion Date

May 31, 2026

Study Completion Date

October 31, 2026

Conditions
Cholangiocarcinoma
Interventions
DRUG

GNS561 + Trametinib

GNS561: 50mg, 100mg, 150mg, 200mg and trametinib: 1mg, 1.5mg and 2mg

Trial Locations (9)

14263

RECRUITING

Roswell Park Cancer Institute, Buffalo

19104

WITHDRAWN

Hospital of the University of Pennsylvania, Philadelphia

22908

RECRUITING

University of Virginia Comprehensive Cancer Center, Charlottesville

53226

RECRUITING

Froedtert Hospital and the Medical College of Wisconsin, Milwaukee

60637

RECRUITING

University Of Chicago Medical Center, Chicago

77030

RECRUITING

University of Texas, MD Anderson Cancer Center, Houston

90033

RECRUITING

USC Norris Comprehensive Cancer Center, Los Angeles

92801

RECRUITING

LA Cancer Network, Los Angeles

00935

RECRUITING

Pan American Center for Oncology Trials, LLC, Rio Piedras

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genfit

INDUSTRY

NCT05874414 - Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma | Biotech Hunter | Biotech Hunter