CXD101 in Immunotherapy-related Liver Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

August 21, 2023

Primary Completion Date

December 30, 2026

Study Completion Date

December 30, 2027

Conditions
HCC
Interventions
DRUG

Zabadinostat (CXD101) and Geptanolimab

"* Zabadinostat (CXD101) at 20mg twice daily per orally Day 1-5 every 3 weeks~* Geptanolimab at 3mg/kg given intravenously every 2 weeks"

DRUG

Lenvatinib and Sorafenib

"Clinicians' choice of TKI at corresponding recommended dosage:~* Lenvatinib at 8mg daily for patients with body weight \<60kg or 12mg daily with body weight ≥ 60kg~* Sorafenib at 400mg twice daily"

Trial Locations (2)

Unknown

RECRUITING

Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong

ACTIVE_NOT_RECRUITING

School of Biomedical Science, The Chinese University of Hong Kong, Hong Kong

All Listed Sponsors
lead

Stephen Chan Lam

OTHER