ACT-TIL and ANV419 for Advanced Melanoma.

PHASE1RecruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

June 21, 2023

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions
Advanced Melanoma
Interventions
DRUG

Combination of Tumor-infiltrating lymphocyte transfer with ANV419

"The study uses a personalized IMP (investigational medicinal product), i.e. TIL product in combination with ANV419.~Day 0: Autologous TIL: (minimum 5 x 10\^9 and up to 2x 10\^11 lymphocytes) administered intravenously over 20 to 30 minutes.~Day 0: Intravenous treatment with ANV419 at 243 μg/kg 2 hours after the TIL infusion. Actual body weight will be used to calculate the dose of ANV419.~Day14: Intravenous treatment with ANV419 at 243 μg/kg. Actual body weight will be used to calculate the dose of ANV419."

Trial Locations (1)

4031

RECRUITING

University Hospital Basel, Basel

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Anaveon AG

INDUSTRY

lead

University Hospital, Basel, Switzerland

OTHER

NCT05869539 - ACT-TIL and ANV419 for Advanced Melanoma. | Biotech Hunter | Biotech Hunter