854
Participants
Start Date
October 21, 2024
Primary Completion Date
December 31, 2027
Study Completion Date
June 30, 2028
SDD
"The intervention group receives SDD treatment additional to standard care, comprising two distinct liquids for oral administration: first the 5 ml amphotericin B suspension (100 mg/ml) and subsequently the 5 ml SDD base for suspension, containing both colistin sulphate (20 mg/ml) and tobramycin sulphate (16 mg/ml).~Patients take the 5 ml amphotericin B, followed by the 5 ml SDD base for suspension, four times daily for one week, starting three days prior to the surgery. On the day of surgery, intake is limited to an early morning and a late evening dose."
RECRUITING
UZ Leuven, Leuven
RECRUITING
Radboudumc, Nijmegen
ZonMw: The Netherlands Organisation for Health Research and Development
OTHER
Universitaire Ziekenhuizen KU Leuven
OTHER
Radboud University Medical Center
OTHER