Cryoanalgesia Study

NACompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

April 10, 2023

Primary Completion Date

July 20, 2024

Study Completion Date

February 13, 2025

Conditions
Pain, Postoperative
Interventions
DEVICE

cryoICE® system (AtriCure, Inc) with CryoSphere (CryoS) probe

Per manufacturer instructions, the cryoprobe will be positioned under direct visualization and ablation of the intercostal nerve will be performed 2-4 cm lateral to the internal mammary artery near the mid-clavicular line. The study team plans to perform each cryoablation (-50°C to -70°C) for 120 seconds to sustain an ablation length of 2-3 cm at each intercostal nerve (bilateral T2 - T6). The probe will be removed after defrosting to avoid mechanical damage to the intercostal nerve. Cryoablation will be performed once hemostasis is achieved and prior to sternal wire placement and chest closure by a provider from the cardiac surgery team.

Trial Locations (1)

60611

Northwestern University, Chicago

All Listed Sponsors
lead

Northwestern University

OTHER