RC1012 Injection (Allo-DNT Cells) for the Prevention of Relapse in AML Patients After Allo-HSCT

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

May 4, 2023

Primary Completion Date

May 27, 2024

Study Completion Date

June 24, 2026

Conditions
Acute Myeloid Leukemia
Interventions
BIOLOGICAL

RC1012 injection (allo-DNT cells)

RC1012 injection (allo-DNT cells) are from healthy donors and have been proved to be safe and demonstrated potent cytotoxicity against AML blasts from AML patients in preclinical and preliminary clinical studies. Allo- DNT cells will be collected from healthy donors (NO MHC match needed) and injected into patients. The drug for this study is an off-the-shelf product. Patients DO NOT need to wait for the cell manufacturing.

Trial Locations (1)

230001

RECRUITING

The First Hospital of the University of Science and Technology of China, Hefei

All Listed Sponsors
collaborator

Anhui Provincial Hospital

OTHER_GOV

lead

Guangdong Ruishun Biotech Co., Ltd

INDUSTRY