Immunogenicity and Safety of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 30 Years and Above

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

924

Participants

Timeline

Start Date

May 7, 2023

Primary Completion Date

December 28, 2024

Study Completion Date

March 31, 2026

Conditions
Herpes Zoster
Interventions
BIOLOGICAL

Low dose Recombinant Herpes Zoster Vaccine (CHO cells)

0.5 mL per dose, containing a total of 50 µg recombinant varicella zoster virus glycoprotein E, adjuvanted with low dose MA105.

BIOLOGICAL

High dose Recombinant Herpes Zoster Vaccine (CHO cells)

0.5 mL per dose, containing a total of 50 µg recombinant varicella zoster virus glycoprotein E, adjuvanted with high dose MA105.

BIOLOGICAL

Positive control

0.5 mL per dose, containing a total of 50 µg recombinant varicella zoster virus glycoprotein E, adjuvanted with AS01B.

BIOLOGICAL

Placebo

0.5 mL per dose, containing 4.5 mg sodium chloride.

Trial Locations (1)

453200

Yanjin Center for Disease Control and Prevention, Xinxiang

All Listed Sponsors
collaborator

Henan Center for Disease Control and Prevention

OTHER_GOV

lead

MAXVAX Biotechnology Limited Liability Company

INDUSTRY

NCT05856084 - Immunogenicity and Safety of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 30 Years and Above | Biotech Hunter | Biotech Hunter