The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

April 30, 2023

Primary Completion Date

August 21, 2023

Study Completion Date

September 21, 2024

Conditions
Diabetic Foot UlcersDiabetic Wound
Interventions
DRUG

Methylene Blue

The first intervention group includes diabetic patients with chronic foot ulcers who, despite common treatments, will be undergone oral methylene blue intervention for 4 weeks.

OTHER

Milk (control)

Group B will receive 200 ml of milk for 4 weeks.

DRUG

Methylene Blue and Platelet-Rich Plasma-Fibrin Glue

Group C will be undergone synergistic 4-week treatment with oral methylene blue and fibrin glue.

OTHER

Milk and Platelet-Rich Plasma-Fibrin Glue (control)

Group D will be treated only with fibrin glue and 200 ml of milk for 4 weeks.

Trial Locations (1)

99191-91778

RECRUITING

Mashhad University of Medical Sciences, Mashhad

All Listed Sponsors
lead

Mashhad University of Medical Sciences

OTHER