NCT05846867 - A Phase Ib/II Clinical Study on AK112 Combined or Not Combined With AK119 in pMMR/MSS Colorectal Cancer | Biotech Hunter

Enrollment

170

Participants

Timeline

Start Date

May 8, 2023

Primary Completion Date

May 8, 2026

Study Completion Date

August 11, 2026

Conditions

Colorectal Cancer

Interventions

DRUG

AK119

AK119 IV every 2 weeks.intravenous infusion

DRUG

AK112

AK112 IV every 2 weeks.intravenous infusion

DRUG

Oxaliplatin

Oxaliplatin: 85mg/m2, intravenous infusion

DRUG

Irinotecan

Irinotecan 180mg/m2, intravenous infusion

DRUG

Calcium folinate

Calcium folinate: 400mg/m2, intravenous infusion

DRUG

Fluorouracil

Fluorouracil 400mg/m2, intravenous injection

Trial Locations (1)

RECRUITING

Cancer Hospital Affiliated to Harbin Medical University, Harbin