Study of PULSAR-ICI +/- IMSA101 in Patients with Oligoprogressive Solid Tumor Malignancies

PHASE2TerminatedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

July 7, 2023

Primary Completion Date

November 20, 2024

Study Completion Date

November 20, 2024

Conditions
Oligoprogressive
Interventions
DRUG

IMSA101

Intra-tumoral administration once weekly for the first three weeks of Cycle 1 (Days 1, 8 and 15) and then on Day 1 of Cycles 2 and 3.

DRUG

Immune checkpoint inhibitor

1st infusion on Cycle 1 Day 2, and then thereafter as per product label.

RADIATION

PULSAR

1st day of Cycles 1, 2 and 3.

Trial Locations (14)

10016

Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York

10461

Montefiore Medical Center, The Bronx

44106

Louis Stokes Cleveland VA Medical Center, Cleveland

44109

MetroHealth Medical Center, Cleveland

53792

University of Wisconsin Hospital and Clinics, Madison

60611

Northwestern Memorial Hospital, Chicago

60637

University of Chicago Medical Center, Chicago

63110

Washington University School of Medicine, St Louis

75390

UT Southwestern Medical Center, Dallas

77030

Baylor College of Medicine Medical Center, Houston

90033

USC/Norris Comprehensive Cancer Center, Los Angeles

90095

UCLA, Los Angeles

92618

City of Hope Orange County Lennar Foundation Cancer Center, Irvine

02115

Brigham and Women's Hospital/Dana Farber Cancer Institute, Boston

Sponsors
All Listed Sponsors
lead

ImmuneSensor Therapeutics Inc.

INDUSTRY