NCT05846594 - A Study to Evaluate the Impact of Liquid Biopsy in Participants With a Clinical Diagnosis of Advanced Cancer | Biotech Hunter

Enrollment

466

Participants

Timeline

Start Date

September 14, 2023

Primary Completion Date

September 6, 2024

Study Completion Date

September 6, 2024

Conditions

Metastatic Lung CancerMetastatic Gastrointestinal Cancer

Interventions

DIAGNOSTIC_TEST

FoundationOne® Liquid CDx Assay

Participants will undergo liquid biopsy (FoundationOne® Liquid CDx) on blood samples collected once they have a clinical diagnosis of advanced cancer (as per label). Blood samples will be tested using the FoundationOne® Liquid CDx assay at a central laboratory. Results of the FoundationOne® Liquid CDx assay will be provided to the investigator to be used in accordance with professional guidelines in oncology for patients with malignant neoplasms.

DIAGNOSTIC_TEST

Standard of Care Diagnostic Pathway

Participants will undergo the local standard of care diagnostic pathway including tissue biopsy/standard of care (if tissue not available), pathology workup, and molecular workup, according to ESMO guidelines or national guidelines for each tumor type included in this study.

Trial Locations (19)

14004

Hospital Universitario Reina Sofia; Servicio de Oncologia, Córdoba

20246

Universitätsklinikum Hamburg-Eppendorf Onkologisches Zentrum Medizinische Klinik II, Hamburg

28027

Clinica Universidad de Navarra Madrid; Servicio de Oncología, Madrid

30625

Med. Hochschule Hannover, Hanover

33100

Azienda Ospedaliero-Universitaria Dipartimento Interaziendale Di Oncologia, Udine

35000

Centre Eugène Marquis, Rennes

37126

Azienda Ospedaliera Universitaria Integrata Verona; UOC Oncologia, Verona

59000

Centre Oscar Lambret; Chir Cancerologie General, Lille

67091

CHU Strasbourg - Nouvel Hopital Civil, Strasbourg

68167

Universität Mannheim; Personalisierte Onkologie, Mannheim

70174

Klinikum Stuttgart - Katharinenhospital, Stuttgart

80131

Università degli Studi della Campania Luigi Vanvitelli; Divsione Di Oncologia Medica, Napoli

81377

Klinikum der LMU München, Campus Großhadern, Krebszentrum München; Comprehensive Cancer Center LMU, München

82131

Asklepios Klinik Gauting; Onkologisches Studienzentrum, Gauting

84918

Institut Sainte Catherine;Recherche Clinique, Avignon

92350

Hopital Marie Lannelongue, Le Plessis-Robinson

94805

Gustave Roussy, Villejuif

98158

Ospedale Papardo- Piemonte;Oncologia Medica, Messina

07014

Hospital Universitario Son Espases; Servicio de Oncologia, Palma de Mallorca