Safety, Tolerability, and Immunogenicity of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Healthy Infants

PHASE2CompletedINTERVENTIONAL
Enrollment

802

Participants

Timeline

Start Date

March 29, 2023

Primary Completion Date

August 25, 2025

Study Completion Date

August 25, 2025

Conditions
Pneumococcal Vaccines
Interventions
BIOLOGICAL

0.5 ml dose of 1.1 mcg VAX-24

24 valent pneumococcal conjugate vaccine

BIOLOGICAL

0.5 ml dose of PCV20

20 valent pneumococcal conjugate vaccine

BIOLOGICAL

0.5 ml dose of 2.2 mcg VAX-24

24 valent pneumococcal conjugate vaccine

BIOLOGICAL

0.5 ml dose of 2.2/4.4 mcg VAX-24

24 valent pneumococcal conjugate vaccine

Trial Locations (32)

15025

UPMC Children's Community Pediatrics South Hills-Jefferson Hills, Jefferson Hills

15213

UPMC Primary Care Center Oakland, Pittsburgh

15217

UPMC Children's Community Pediatrics Bass Wolfson-Squirrel Hill, Pittsburgh

15234

UPMC Children's Community Pediatrics-Castle Shannon, Pittsburgh

16066

UPMC Bass Wolfson Cranberry, Cranberry Township

16506

Allegheny Health and Wellness Pavilion, Erie

22902

Pediatric Research of Charlottesville, LLC, Charlottesville

29406

Palmetto Pediatrics, PA, North Charleston

29486

Coastal Pediatric Research, Summerville

29680

Tribe Clinical Research at Parkside Pediatrics, Simpsonville

33617

Jedidiah Clinical Research, Tampa

37660

Holston Medical Group, Kingsport

40004

Kentucky Pediatric/ Adult Research, Bardstown

45414

Ohio Pediatric Research Assn., Dayton

68504

Midwest Children's Health Research Institute, Lincoln

68505

Midwest Children's Health Research Institute, Lincoln

68516

Midwest Children's Health Research Institute, Lincoln

68522

Midwest Children's Health Research Institute, Lincoln

68901

Meridian Clinical Research, Hastings

71037

ACC Pediatric Research, Haughton

72401

The Children's Clinic of Jonesboro, P.A., Jonesboro

76028

Ventavia Research Group, Burleson

77008

Ventavia, Houston

77065

Kool Kids Pediatrics, Houston

77087

Pediatric Associates, Houston

77469

Pediatric Center, Richmond

84041

Alliance for Multispecialty Research, Layton

84067

Alliance for Multispecialty Research, Roy

84075

Alliance for Multispecialty Research, Syracuse

84107

Alliance for Multispecialty Research, Murray

84604

Alliance for Multispecialty Research, Provo

93637

Madera Family Medical Group, Madera

All Listed Sponsors
lead

Vaxcyte, Inc.

INDUSTRY