64
Participants
Start Date
April 14, 2023
Primary Completion Date
July 28, 2023
Study Completion Date
July 28, 2023
Vorasidenib 40 mg Oral Tablet
"Single oral dose of 1×40 mg vorasidenib tablet administered :~* under fasted conditions (all subjects will fast overnight for at least 10 hours prior to dosing and for at least 4 hours after dosing.~* or following a low fat meal (approximatively 400 to 500 calories) (Substudy A)"
Ciprofloxacin 500 mg Oral Tablet
Twice daily (morning and evening) oral doses of ciprofloxacin 1×500 mg tablet on Days 1 through 14 (Substudy B)
Vorasidenib 10 mg Oral Tablet
Single oral dose of vorasidenib 2×10 mg tablets administered on Day 1 (Substudy B)
PPD Development, Austin
Institut de Recherches Internationales Servier
OTHER
Servier Bio-Innovation LLC
INDUSTRY