HEALEY ALS Platform Trial - Regimen G DNL343

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

249

Participants

Timeline

Start Date

May 24, 2023

Primary Completion Date

October 29, 2024

Study Completion Date

October 29, 2024

Conditions
Amyotrophic Lateral Sclerosis
Interventions
DRUG

DNL343

DNL343 is administered orally once daily per day for 24 weeks.

DRUG

Matching Placebo

Matching placebo is administered orally once daily per day for 24 weeks.

Trial Locations (1)

02114

Healey Center for ALS at Massachusetts General Hospital, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Denali Therapeutics Inc.

INDUSTRY

lead

Merit E. Cudkowicz, MD

OTHER

NCT05842941 - HEALEY ALS Platform Trial - Regimen G DNL343 | Biotech Hunter | Biotech Hunter