NCT05842291 - pBFS Guided High-dose rTMS Therapy for Treatment-Resistant Depression | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

June 19, 2023

Primary Completion Date

August 1, 2024

Study Completion Date

November 1, 2024

Conditions

Treatment-Resistant Depression

Interventions

DEVICE

Active rTMS with short inter-session interval

Participants in this group will receive ten sessions per day of 1800 pulses per session, at an inter-session interval of 20 min for 5 days. The individualized target will be generated using the personalized Brain Functional Sectors (pBFS) method.

DEVICE

Sham rTMS with short inter-session interval

Participants in this group will receive ten sessions per day of 1800 pulses per session, at an inter-session interval of 20 min for 5 days, using sham stimulation coils that comprehensively mimic the active condition. The individualized target will be generated using the personalized Brain Functional Sectors (pBFS) method.

DEVICE

Active rTMS with long inter-session interval

Participants in this group will receive ten sessions per day of 1800 pulses per session, at an inter-session interval of 50 min for 5 days. The individualized target will be generated using the personalized Brain Functional Sectors (pBFS) method.

Trial Locations (1)

100096

RECRUITING

Beijing HuiLongGuan Hospital, Beijing