NCT05841394 - A Multi-center, Double-blinding, Parallel and Positive-controlled Phase III Clinical Trial for Efficacy and Safety Evaluation of Ilaprazole Sodium for Injection on Prevention of Stress Ulcer Bleeding | Biotech Hunter

Enrollment

449

Participants

Timeline

Start Date

July 16, 2021

Primary Completion Date

April 28, 2022

Study Completion Date

April 28, 2022

Conditions

Stress Ulcer Bleeding

Interventions

DRUG

Esomeprazole 40mg

40 mg i.v. twice daily (q12h)

DRUG

Ilaprazole Sodium

10 mg i.v. once daily, 20 mg i.v. in the first day.

DRUG

Placebo 1

Physiologic saline for injection, 100 ml/bag, q24h, following Ilaprazole Sodium with a time interval of 12 h.

DRUG

Placebo 2

Physiologic saline for injection, 100 ml/bag, q12h, dosing on the first day.

Trial Locations (2)

Shanghai Jiaotong University Affiliate Ruijin Hospital, Shanghai

The First Affiliated Hopspital of Xinjiang Medical University, Ürümqi