Tranexamic Acid as an Intervention in Abruptio Placenta

NACompletedINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

January 10, 2023

Primary Completion Date

February 2, 2024

Study Completion Date

February 10, 2024

Conditions
Vaginal BleedingProlonged Pregnancy
Interventions
DRUG

Tranexamic acid injection

This interventional arm will receive tranexamic acid 1 g(10ml) (2 ampules each of 500 mg, 5ML) of tranexamic acid in 20 ml glucose water 5% intravenously twice daily in the acute stage of bleeding for 48 hours. This will be followed by 500 mg tranexamic acid tablets (Trenaxa; Macleods Pharmaceuticals Pvt. Ltd.) three times daily for five days. Participants will be followed up for recurrence of bleeding during pregnancy. The course of treatment will be repeated again if bleeding recurred. The hospital data safety and monitoring board ensured the continued safety of the Participants.

OTHER

Glucose water 5%

This interventional arm will receive tranexamic acid 1 g(10ml) (2 ampules each of 500 mg, 5ML) of tranexamic acid in 20 ml glucose water 5% intravenously twice daily in the acute stage of bleeding for 48 hours. This will be followed by 500 mg tranexamic acid tablets (Trenaxa; Macleods Pharmaceuticals Pvt. Ltd.) three times daily for five days. Participants will be followed up for recurrence of bleeding during pregnancy. The course of treatment will be repeated again if bleeding recurred. The hospital data safety and monitoring board ensured the continued safety of the Participants.

Trial Locations (1)

44001

Shahla Kareem Alalaf, Erbil

All Listed Sponsors
lead

Hawler Medical University

OTHER