RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 20, 2023

Primary Completion Date

July 31, 2025

Study Completion Date

December 31, 2025

Conditions
Chronic Spinal Pain
Interventions
DEVICE

Magstim Rapid2

"1-4 weeks after administration of the SJI, participants will attend their first rTMS session. rTMS will be delivered using a biphasic stimulator (DuoMag) and a figure-of-eight coil to the corticomotor representation of the first dorsal interosseous muscle contralateral to the side of worst pain. Recording electrodes will be positioned in a belly-tendon montage over the FDI for electromyography recording. The hotspot and resting motor threshold (rMT) of the FDI will be determined and saved using a Brainsight Neuronavigation system to ensure accurate coil repositioning within and between sessions.~The hotspot and rMT will be confirmed and adjusted if needed at each intervention session. Each rTMS session will consist of 40 trains of 5s delivered at 10Hz, at an intensity of 85% of the resting motor threshold for the FDI muscle and an intertrain interval of 25s (total of 2000 stimulations in a 20-minute session)."

DEVICE

Placebo D70mm Air Film Coil

Sham intervention will follow same protocol as active rTMS using a sham coil that does not deliver actual magnetic stimulation.

Trial Locations (2)

N6A4V2

RECRUITING

St. Joseph's Health Care London, London

N6C 0A7

RECRUITING

Parkwood Institute (Main Building), London

All Listed Sponsors
collaborator

Western University, Canada

OTHER

collaborator

St. Joseph's Health Care London

OTHER

lead

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

OTHER