NCT05839730 - Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction | Biotech Hunter

Enrollment

105

Participants

Timeline

Start Date

September 11, 2024

Primary Completion Date

July 31, 2026

Study Completion Date

July 31, 2027

Conditions

Heart Failure With Preserved Ejection FractionConcentric Hypertrophy

Interventions

DEVICE

Pacemaker PLR + TRT ON

RAMware modified implantable pulse generator (IPG) with personalized lower rate (PLR) and tachycardia remodeling therapy (TRT) ON

DEVICE

Pacemaker non-pacing mode or an exertional rate-adaptive pacing mode with no planned pacing at rest.

RAMware modified implantable pulse generator (IPG)

Trial Locations (9)

27708

RECRUITING

Duke University, Durham

34102

RECRUITING

NCH Heart Institute, Naples

62269

RECRUITING

Prairie Education and Research Cooperative-St. Elizabeth's, O'Fallon

62769

RECRUITING

Prairie Education and Research Cooperative-St. John's, Springfield

66160

RECRUITING

University of Kansas Medical Center, Kansas City

73120

RECRUITING

Oklahoma Heart Hospital, Oklahoma City

75216

NOT_YET_RECRUITING

Dallas VA Medical Center, Dallas

77030

RECRUITING

Houston Methodist Research Institute, Houston

05401

RECRUITING

The University of Vermont Medical Center, Burlington

All Listed Sponsors

lead

Medtronic Cardiac Rhythm and Heart Failure

INDUSTRY