A Trial of YPEG-rhGH in Children With Short Stature

PHASE2CompletedINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

February 15, 2022

Primary Completion Date

October 23, 2023

Study Completion Date

December 19, 2023

Conditions
Idiopathic Short StatureSmall for Gestational AgeTurner Syndrome
Interventions
DRUG

YPEG-rhGH

YPEG-rhGH, 140μg/kg, s.c., once a week, for 52 weeks

DRUG

YPEG-rhGH

YPEG-rhGH, 280μg/kg, s.c., once a week, for 52 weeks

DRUG

rhGH

rhGH, 245μg/kg/week, divided into 7 subcutaneous injections, once daily, for 52 weeks

DRUG

rhGH

rhGH, 470μg/kg/week, divided into 7 subcutaneous injections, once daily, for 52 weeks

Trial Locations (19)

Unknown

The Fourth Affiliated Hospital of Anhui Medical University, Hefei

The Second Hospital of Anhui Medical University, Hefei

The First Affiliated Hospital of Xiamen University, Xiamen

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou

The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou

Sanya Central Hospital (Hainan Third People's Hospital), Sanya

Henan Children's Hospital Zhengzhou Children's Hospital, Zhengzhou

Tongji Hospital, Tongji Medical College of HUST, Wuhan

Wuhan Children's Hospital, Wuhan

Hunan Children's Hospital, Changsha

Children's Hospital of Nanjing Medical University, Nanjing

Children's Hospital of Soochow University, Suzhou

Affiliated Hospital of Jiangnan University, Wuxi

Jiangxi Provincial Children's Hospital, Nanchang

Chengdu Women's and Children's Central Hospital, Chengdu

West China Second University Hospital, Sichuan University, Chengdu

Zhejiang Provincial People's Hospital, Hangzhou

Children's Hospital, Capital Institute of Pediatrics, Beijing

Children's Hospital of Shanghai, Shanghai

All Listed Sponsors
collaborator

Tongji Hospital

OTHER

lead

Xiamen Amoytop Biotech Co., Ltd.

INDUSTRY