'Optiflow + Duet' Interface' vs 'Standard' High Flow Nasal Cannula

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 8, 2023

Primary Completion Date

June 30, 2023

Study Completion Date

July 30, 2023

Conditions
Hypoxemia
Interventions
DEVICE

Symmetrical high flow nasal cannula (HFNO)

"After a 'baseline' trial using Venturi Mask, within the first 120 minutes after extubation, and assessing a PaO2/FiO2 ratio \< 300, patients will be randomly assigned to a first 1h-phase of 'conventional HFNO' or 'DUET HFNO'. At the end of each session several clinical parameters (i.e. DUS, EIT, ABGs, comfort, VAS) will be collected.~Specifically, Gas-flow rate will be set at a maximum of 60 L/min, temperature at a maximum of 37°C, while FiO2 will be adjusted to maintain SpO2 between 92 and 98%."

DEVICE

Asymmetrical high flow nasal cannula (DUET HFNO)

"After a 'baseline' trial using Venturi Mask, within the first 120 minutes after extubation, and assessing a PaO2/FiO2 ratio \< 300, patients will be randomly assigned to a first 1h-phase of 'DUET HFNO' vs 'conventional HFNO'. At the end of each session several clinical parameters (i.e. DUS, EIT, ABGs, comfort, VAS) will be collected.~Specifically, Gas-flow rate will be set at a maximum of 60 L/min, temperature at a maximum of 37°C, while FiO2 will be adjusted to maintain SpO2 between 92 and 98%.~A 5-10min 'washout' phase using VM, between different interfaces, will be allowed."

Trial Locations (1)

35120

Institute of Anaesthesia and Intensive Care, Padua University hospital, Padua

All Listed Sponsors
lead

University of Padova

OTHER

NCT05838326 - 'Optiflow + Duet' Interface' vs 'Standard' High Flow Nasal Cannula | Biotech Hunter | Biotech Hunter