672
Participants
Start Date
August 1, 2024
Primary Completion Date
August 31, 2028
Study Completion Date
August 31, 2029
Atorvastatin Calcium
Capsule, 80 mg/day, with no loading dose, for 28 days
Minocycline Hydrochloride
Capsule, 200 mg loading dose on Day 1, then 100 mg twice daily for 6 days, then placebo twice daily for 21 days
Candesartan Cilexetil
Capsule, 8 mg once on Day 1, then 16 mg daily for 27 days
Placebo
Capsule, 2x/day for 28 days
University of Pittsburgh, Pittsburgh
University of Pennsylvania, Philadelphia
Duke University Medical Center, Durham
Atrium Health Wake Forest Baptist, Charlotte
Vanderbilt University Medical Center, Nashville
University of Kentucky, Lexington
University of Cincinnati Medical Center, Cincinnati
Indiana University Health, Indianapolis
UW Health University Hospital, Madison
Baylor College of Medicine, Houston
UTHealth Houston, Houston
The University of Texas at Austin, Austin
University of Utah, Salt Lake City
University of California, San Francisco, San Francisco
University of Washington, Seattle
United States Department of Defense
FED
University of California, San Francisco
OTHER