Priming Motor Learning Through Exercise in People With Spinocerebellar Ataxia

NAActive, not recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 6, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

May 31, 2025

Conditions
Spinocerebellar Ataxia Type 1Spinocerebellar Ataxia Type 2Spinocerebellar Ataxia Type 3Spinocerebellar Ataxia Type 6Spinocerebellar Ataxia Type 7
Interventions
BEHAVIORAL

High-Intensity Aerobic Exercise Prior to Balance Training

20-30 minutes of high intensity aerobic exercise followed by 20-30 minutes of individualized balance training over telehealth twice weekly, for 8 weeks (16 sessions total). For the aerobic component, participants will be instructed in a 20-30-minute exercise program, using available equipment already located in the participant's home (eg. stationary cycle, elliptical trainer, etc). Exercise intensity is moderate-to-high (between 50-85% Heart Rate Reserve. Participants will be placed on a ramped protocol which increases in intensity slowly over the course of the intervention period. For the balance training component, exercises will consist of steady state, proative, and reactive balance activities that involve sensory integration of vision, proprioception, and vestibular senses. Exercises will be individualized based on baseline assessment outcomes and severity of ataxia as rated by the SARAHome.

BEHAVIORAL

Low-Intensity Exercise Prior to Balance Training

"20-30 minutes of light intensity warm-up type exercises, followed by 20-30 minutes of individualized balance training over telehealth twice weekly, for 8 week (16 sessions total). For the warm-up exercise component, exercises will consist of stretching and core training. For the balance training component, exercises will consist of steady state, proactive, and reactive balance activities that involve sensory integration of vision, proprioception, and vestibular senses throughout. Exercises will be individualized based on baseline assessment outcomes and severity of ataxia as rated by the SARAHome.~Both groups are matched for time and frequency of intervention components."

Trial Locations (1)

10027

Teachers College, Columbia University, New York

All Listed Sponsors
lead

Teachers College, Columbia University

OTHER