40
Participants
Start Date
June 14, 2023
Primary Completion Date
January 31, 2026
Study Completion Date
January 31, 2026
Selexipag
If Arm A - Up-titration to maximum tolerated dose followed by de-escalation If Arm B - Up-titration to maximum tolerated dose followed by observation, modification or transition at discretion of responsible care team where necessary.
Riociguat
If Arm A - Up-titration to maximum tolerated dose followed by de-escalation If Arm B - Up-titration to maximum tolerated dose followed by observation, modification or transition at discretion of responsible care team where necessary.
CardioMEMS pulmonary artery pressure monitor
Implantation and remote monitoring established with patient initiated daily readings
Confirm Rx
Implantation and remote monitoring established with automated daily readings / downloads
RECRUITING
Sheffield Teaching Hospitals NHS FT, Sheffield
University of Glasgow
OTHER
University of Sheffield
OTHER
University of Newcastle Upon-Tyne
OTHER
University of Cambridge
OTHER
Sheffield Teaching Hospitals NHS Foundation Trust
OTHER