Efficacy of Suvorexant on Post-operative Sleep Disturbance

PHASE4RecruitingINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

May 1, 2023

Primary Completion Date

May 31, 2025

Study Completion Date

May 31, 2025

Conditions
Postoperative InsomniaPostoperative Delirium
Interventions
DRUG

Suvorexant

Suvorexant (Belsomra™) is an orexin receptor antagonist that will be administered as 2 tablets (10mg each) for a starting dose of 20mg. If the dose is not well tolerated (e.g., daytime sleepiness), then the dose may be decreased to 10 mg of Suvorexant.

DRUG

Placebo

The placebo pill will look identical to Suvorexant and will be taken as 2 tablets.

Trial Locations (1)

10032/10034

RECRUITING

NewYork-Presbyterian Allen Hospital/CUMC Milstein Hospital Building, New York

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Columbia University

OTHER