A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

February 14, 2023

Primary Completion Date

April 1, 2028

Study Completion Date

October 15, 2028

Conditions
Spinocerebellar Ataxia Type 1Spinocerebellar Ataxia Type 3Huntington Disease
Interventions
DRUG

VO659

VO659 is an antisense oligonucleotide targeting CAG repeats in mRNA transcripts

Trial Locations (14)

Unknown

RECRUITING

Rigshospitalet, Copenhagen

RECRUITING

Centre Hospitalier Universitaire dÁngers, Angers

RECRUITING

CHU Gui de Chauliac Montpellier- Expert Center of Neurogenetic diseases, Department of Neurology, Montpellier

RECRUITING

Universtiry Hospitals Pitie Salpetriere - Charles foix - Paris, Paris

RECRUITING

Katholisches Klinikum Bochum, Bochum

RECRUITING

Deutsches Zentrum fur Neurodegenerative Erkrankungen (DZNE), Bonn

RECRUITING

Universitatsklinikum Essen - Neurologie, Essen

RECRUITING

Universitatsklinikum Tübingen, Tübingen

RECRUITING

Meir Medical Center, Kfar Saba

RECRUITING

Sourmansky Medical Center, Tel Aviv

RECRUITING

Leiden University Medical Center LUMC, Leiden

RECRUITING

Radbout University Medical Centre, Nijmegen

RECRUITING

University College London Hospitals NHS Foundation, London

RECRUITING

John Radcliffe Hospital, Oxford

All Listed Sponsors
lead

Vico Therapeutics B. V.

INDUSTRY