161
Participants
Start Date
August 21, 2023
Primary Completion Date
June 28, 2024
Study Completion Date
June 28, 2024
Molnupiravir
Four molnupiravir 200 mg capsules (800 mg total dose) taken twice daily by mouth.
Placebo molnupiravir
Four placebo capsules matched to molnupiravir taken twice daily by mouth.
Placebo oseltamivir
Placebo capsule matched to oseltamivir taken twice daily by mouth.
Oseltamivir
One capsule of oseltamivir 75 mg taken twice daily by mouth.
Influenza A Virus
Influenza A challenge virus given once by intranasal administration at an inoculum concentration of between approximately 5 and 7 Log10 tissue culture infective dose 50% (TCID50/mL).
hVIVO Services ( Site 0001), London
Merck Sharp & Dohme LLC
INDUSTRY