Clinical Study of Azacitidine Combined With Ruxolitinib in the Treatment of Higher-risk MDS/MPN

PHASE2RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 1, 2022

Primary Completion Date

January 1, 2025

Study Completion Date

December 30, 2026

Conditions
MDS/MPN
Interventions
DRUG

Azacitidine (AZA) with Ruxolitinib

"1. Antibiotics: Antibiotic treatment is positively given when symptoms related to infection, and other support treatment is strengthened.~2. Blood products: Infuse the blood products according to the patient's blood routine test. Drugs that need to be used by other diseases must be recorded in detail in the case report form, including the general name of the drug, the dosage of the medication, and the frequency of administration. Drugs are not allowed to be combined: Avoiding the use of granulocyte colony-stimulating factor (G-CSF), there may be risk of spleen rupture."

Trial Locations (1)

210000

RECRUITING

The First Affiliated Hospital of Nanjing Medical University, Nanjing

All Listed Sponsors
collaborator

Jiangbin Hospital Affiliated to Jiangsu University

UNKNOWN

collaborator

Nanjing Second Hospital

UNKNOWN

collaborator

Jiangning Hospital Affiliated to Nanjing Medical University

UNKNOWN

lead

The First Affiliated Hospital with Nanjing Medical University

OTHER