A Cohort Prospective Study of Predictors Influencing the Quality of Visualization of the Operating Field During Orthognathic Surgery

Enrolling by invitationOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

May 29, 2023

Primary Completion Date

January 15, 2026

Study Completion Date

June 15, 2026

Conditions
MalocclusionMaxillofacial InjuriesOrthodonticsHemorrhage
Interventions
DRUG

Nitroglycerin solution

Controlled hypotension will be induced (intravenous administration of nitroglycerin 2-10 µg/kg/min) 15 minutes prior to the start of mucosal detachment, and will be sustained for the osteotomy stage.

DEVICE

monitoring of cerebral oxygen saturation

NIRS-based monitoring of rSO2 has unique advantages: directly or indirectly detecting physiological changes and metabolic processes, it is easy to realize, and involves simple procedures.

Trial Locations (1)

105203

Pirogov National Medical and Surgical Center, Moscow

All Listed Sponsors
lead

State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia

OTHER