0.9% Saline Versus Balanced Solutions in Severe Diabetic Ketoacidosis

PHASE4CompletedINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

November 1, 2022

Primary Completion Date

December 30, 2023

Study Completion Date

December 30, 2023

Conditions
Metabolic KetoacidosisKetoacidemiaAcetonemiaAcetonuria
Interventions
DRUG

Sodium chloride 0.9% (SC)

This trial looks specifically at the type of hydratation liquid. The patients included will receive SC. The volume, frequency of fluid administration and other severe DKA therapies, such as insulin therapy and electrolytes, are prescribed similarly. The intervention will continue for 48 hours from admission to the ICU with a blood gas control (including base excess) + Blood glucose + ionogram (Na, K, chlorine) + lactates on admission (or H0), H6, H12, H24 and H48.

DRUG

Ringer lactate (RL)

The intervention will continue for 48 hours from admission to the ICU with a blood gas control (including base excess) + Blood glucose + ionogram (Na, K, chlorine) + lactates on admission (or H0), H6, H12, H24 and H48.

Trial Locations (1)

1007

Ahlem Trifi, Tunis

All Listed Sponsors
lead

Tunis University

OTHER

NCT05808972 - 0.9% Saline Versus Balanced Solutions in Severe Diabetic Ketoacidosis | Biotech Hunter | Biotech Hunter