To Understand the Safety and Effects of a C. Difficile Vaccine With New Adds-Ons That Will Be Given to Healthy Adults

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

689

Participants

Timeline

Start Date

March 23, 2023

Primary Completion Date

August 28, 2028

Study Completion Date

August 28, 2028

Conditions
Clostridoides Difficile Associated Disease
Interventions
BIOLOGICAL

C. difficile vaccine (previously studied formulation).

Toxoid based Clostridioides difficile vaccine (previously studied formulation) given as an intramuscular injection

BIOLOGICAL

C. difficile vaccine formulation 1.

C. difficile vaccine formulation 1 given as an intramuscular injection

BIOLOGICAL

C. difficile vaccine formulation 2.

C. difficile vaccine formulation 2 given as an intramuscular injection

BIOLOGICAL

C. difficile vaccine formulation 3.

C. difficile vaccine formulation 3 given as an intramuscular injection

OTHER

Saline Placebo.

0.9% sodium chloride solution given as an intramuscular injection

Trial Locations (25)

10016

NYU Langone Health, New York

14609

Rochester Clinical Research, LLC, Rochester

33012

Indago Research & Health Center, Inc, Hialeah

33014

Charisma Medical and Research Center, Miami Lakes

33024

Research Centers of America ( Hollywood ), Hollywood

Research Centers of America, Hollywood

33026

Private Practice - Dr. Hector Fabregas, Pembroke Pines

33029

DBC Research USA, Pembroke Pines

33134

Alliance for Multispecialty Research, LLC, Coral Gables

33155

Miami Clinical Research, Miami

33165

New Horizon Research Center, Miami

33322

BRCR Medical Center Inc., Plantation

33607

Clinical Research Trials of Florida, Tampa

45212

CTI Clinical Research Center, Cincinnati

55114

Prism Research LLC dba Nucleus Network, Saint Paul

60031

Great Lakes Clinical Trials - Gurnee, Gurnee

60640

Great Lakes Clinical Trials - Ravenswood, Chicago

63110

Washington University School of Medicine, St Louis

67207

Alliance for Multispecialty Research, LLC, Wichita

77375

DM Clinical Research - MDC, Tomball

78705

Benchmark Research, Austin

85018

Hope Research Institute, Phoenix

The Pain Center of Arizona, Phoenix

85032

HOPE Research Institute, Phoenix

92801

Anaheim Clinical Trials, LLC, Anaheim

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT05805826 - To Understand the Safety and Effects of a C. Difficile Vaccine With New Adds-Ons That Will Be Given to Healthy Adults | Biotech Hunter | Biotech Hunter